Hello @matthew55, thank you for the question.
There are pair restrictions as well as regional and fiat considerations that may limit your trading options. We provide the ability to pair against USD, USDC, GBP, and EUR in an attempt to give a variety of options. But some customers may still find some limits.
I may also note that Auto Trade would only be active for one pair at a time.
Last, Binance Auto Trade support is going through final QA this week. We expect it to be live this weekend or first thing next week. Binance has broader pairing options and maybe a good solution for those who are limited in Coinbase Pro.